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beta-glucan 1,3-D

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My investigation into this nutritional item includes these quotations:

What is Beta Glucan?

Beta Glucan is a unique compound derived from the cell walls of yeast. Beta Glucan triggers an immune response in the body creating a system of defense against viral, bacterial, fungal, and parasitic or neoplastic invaders. It also has potent anti-oxidant and free radical scavenging capabilities.

History of Beta Glucan

In the 1940s research yielded a substance that had immune activating properties called Zymosan. It was not known until the 1960s which element caused the response, when Nicholas DiLuzio at Tulane University experimented with Beta-1, 3-D Glucan. In the 1970s, experiments with Beta-1, 3-D Glucan in humans began.

Common Questions About Beta Glucan

What is beta glucan?
Beta Glucan is a compound extracted from the cell walls of a baker’s yeast, with extraordinary immune enhancing capabilities.

Is it safe?
Beta glucan is completely safe and nontoxic.

I am allergic to yeast. Will this cause a problem?
Although derived from a baker’s yeast, beta glucan is a pure isolate and does not contain any yeast proteins that would cause an allergic reaction.

Are there any drug reactions that occur with Beta Glucan?
Beta Glucan enhances the effect of many antibiotic and cholesterol reducing drugs. There are no known adverse effects with pharmacological drugs.

Are the effects of beta glucan backed by scientific research?
Numerous scientific studies originating from prestigious institutions such as Tulane University and Harvard Medical School, attest to the immune activating and protective effects of beta glucan.

Are glucans from barley, oats, or other grains as effective as the beta glucans derived from bakers yeast?
 They have been shown to be ineffective as an immune modulator. Only Beta-1, 3-D glucan from the cell wall of baker's yeast has been shown to have a potent effect on the immune system, in an economical manner.

When the BETA GLUCAN molecule is absorbed into the cell, does the molecular structure remain the same?
The Beta glucan molecule is not absorbed into the cells. There are receptors on the surface of neutrohils, macrophages and other phagocytes (immune cells). Once the Beta glucan particle comes in proximity to these receptors, they become more attentive. A cascade of events occur to turn the glucan treated host into "an arsenal of defense", says Czop from Harvard. The particulate from the Beta glucan do not physically go inside the cell and do anything. Again, we are talking about a non-chemical process.

So considering the question, "How does Beta glucan get through the blood brain barrier?" We do not have to get Beta glucan across a blood brain barrier. What does cross the blood brain barrier is the communication between our white blood cells, through interferon, interleukins, and in the area of cancers, Tumor Necrosis Factor (TNF). Also, let's not forget there is a communication between certain white blood cells and autonomic nerves.  Not only do we have communication via chemical fax messages that occur back and forth between the cells, we also have responses between the white blood cells and our autonomic nerve cells.

Yes, if you get depressed or some other mental issue wears on you, it will affect the immune system.

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"An apple a day may keep the doctor away, but results of a recent human clinical study suggest far better results may be obtained with a dietary supplement called Beta Glucan 1,3-D. Beta Glucan 1,3-D is a highly purified and patented carbohydrate extracted from the cell walls of Baker’s yeast.

An independent study conducted by Biophage Pharma Inc., a Canadian biopharmaceutical company, treated normal human volunteers with 250 milligrams of Beta Glucan 1,3-D for 10 consecutive days. The subjects were monitored for 30 days. The results of the human clinical study found that the Beta Glucan 1,3-D was safe and well tolerated, as evidenced by the lack of significant changes in key blood and liver enzymes. It also significantly increased phagocytic capacity—the ability of the innate immune cells to eat and destroy foreign intruders. On day ten of the study Beta Glucan had increased the percentage of immune cells able to phagocytose one target particle from 63.8 percent to 83.2 percent. The number of highly phagocytic cells —those consuming at least three particles—increased from 37.3 percent to more than 50 percent. These results show that taking Beta Glucan enhanced the human immune system to defend the body against a challenge.

The results are consistent with the biological activity of Beta Glucan 1,3-D observed in numerous animal studies,” said Rosemonde Mandeville, Chief Scientific Officer of Biophage Pharma. In addition, researchers also found that Beta Glucan 1,3-D increased plasma cytokines INF-y and TNF-a, which play an important role in regulating the body’s immune response. There was no significant increase in cytokine IL-1, which can cause fever, chills and muscle aches associated with other immune-enhancing supplements."

This may be the most potent immune system builder ever.

Learn More About VitaBase Beta Glucan